Department of Medical Statistics, University Goettingen

Priv.-Doz. Dr. Steffen Unkel, MSc in Statistics


Senior Research Associate - WG Clinical Trials
Phone:
+49 (0)551-39-4956
Telefax:
+49 (0)551-39-4995
E-Mail:
Steffen.Unkel@med.uni-goettingen.de
Office room:
Humboldtallee 32, Floor 1, 132
ORCID iD:
 orcid.org/0000-0002-2083-0090

Teaching

Winter term 2019/20 Summer term 2019 Some previously held courses Munich R courses
Research Interests


Third-party funding


Memberships


Short CV

06/2018 Venia Legendi in Statistics - Medical Faculty, Georg-August-University Göttingen
01/2017 Habilitation in Statistics - Faculty of Mathematics, Informatics and Statistics, Ludwig-Maximilians-University Munich
since 07/2014 Research Fellow, Department of Medical Statistics,
University Medical Center, Georg August University Göttingen
04/2013 - 02/2014 Visting Associate Professor of Statistics, Department of Statistics,
Ludwig-Maximilians-University Munich
04/2012 - 06/2014 Research Fellow, Institut of Medical Informatics,
Justus-Liebig-University Giessen
10/2009 - 03/2012 Post-Doctoral Research Fellow
Department of Mathematics and Statistics, The Open University, United Kingdom
10/2006 - 09/2009 PhD in Statistics
Department of Mathematics and Statistics, The Open University, United Kingdom
10/2004 - 07/2005 MSc in Statistics
University of London - London School of Economics, United Kingdom
05/2002 - 09/2006 Research Assistant
Department of Statistics and Econometrics, University of Siegen
09/1994 - 04/2002 Diplom-Volkswirt and Diplom Kaufmann
Department of Economics, University of Siegen

Publications

  1. Unkel S., Amiri M., Benda N., Beyersmann J., Knoerzer D., Kupas K., Langer F., Leverkus F., Loos A., Ose C., Proctor T., Schmoor C., Schwenke C., Skipka G., Unnebrink K., Voss F. and Friede T. (2019): On estimands and the analysis of adverse events in the presence of varying follow-up times within the benefit assessment of therapies, Pharmaceutical Statistics, Vol. 18, pp. 166-183.


  2. Friede T., Posch M., Zohar S., Alberti C., Benda N., Comets E., Day S., Dmitrienko A., Graf A., Günhan B. K., Wan Hee S., Lentz F., Madan J., Miller F., Ondra T., Pearce M., Röver C., Toumazi A., Unkel S., Ursino M., Wassmer G. and Stallard N. (2018): Recent advances in methodology for clinical trials in small populations: the InSPiRe project, Orphanet Journal of Rare Diseases, 13:186.


  3. Krombach J., Hennel R., Brix N., Orth M., Schoetz U., Ernst A., Schuster J., Zuchtriegel G., Reichel C. A., Bierschenk S., Sperandio M., Vogl T., Unkel S., Belka C. and Lauber K. (2018): Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells, OncoImmunology, in press.


  4. Djukic M., Braun L. M., Unkel S., Jacobshagen C. and Nau R. (2018): Introduction of non-vitamin K antagonist anticoagulants strongly increased the rate of anticoagulation in geriatric patients, Drugs & Aging, Vol. 35, pp. 859-869.


  5. Unkel S. (2017): On the shape of the cross-ratio function in bivariate survival models induced by truncated and folded normal frailty distributions, Metrika, Vol. 80, pp. 351-362.


  6. Unkel S. (2017): On the conditional probability for assessing time dependence of association in shared frailty models with bivariate current status data, Journal of Statistical Planning and Inference, Vol. 182, pp. 1-11.


  7. Unkel S., Röver C., Stallard N., Benda N., Posch M., Zohar S. and Friede, T. (2016): Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions, Orphanet Journal of Rare Diseases, 11:16.


  8. Unkel S., Belka C. and Lauber K. (2016): On the analysis of clonogenic survival data: Statistical alternatives to the linear-quadratic model, Radiation Oncology, 11:11.


  9. Ernst A., Kapfhammer H., Anders H., Orth M., Hennel R., Seidl K., Winssinger, N., Belka C., Unkel S. and Lauber K. (2015): HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas, Cancer Letters, Vol. 365, Issue 2, pp. 211-222.


  10. Kiessling J., Leifholz M., Unkel S., Pons-Kühnemann J., Thunberg C. and Pedersen J. N. (2015): A Comparison of Conventional and In-Situ Audiometry on Participants with Varying Levels of Sensorineural Hearing Loss, Journal of the American Academy of Audiology, Vol. 26, pp. 68-79.


  11. Unkel S., Farrington C. P., Whitaker H. J. and Pebody R. (2014): Time-varying frailty models and the estimation of heterogeneities in transmission of infectious diseases, Journal of the Royal Statistical Society Series C, Vol. 63, pp. 141-158.


  12. Farrington C. P., Unkel S. and Anaya-Izquierdo K. (2013): Estimation of basic reproduction numbers: individual heterogeneity and robustness to perturbation of the contact function, Biostatistics, Vol. 14, pp. 528-540.


  13. Unkel S. and Trendafilov N. T. (2013): Zig-zag exploratory factor analysis with more variables than observations. Computational Statistics, Vol. 28, pp. 107-125


  14. Trendafilov N. T., Unkel S. and Krzanowski W. J. (2013): Exploratory factor and principal component analyses: some new aspects. Statistics and Computing, Vol. 23, pp. 209-220.


  15. Farrington C. P., Whitaker H. J., Unkel S. and Pebody, R. (2013): Correlated infections: quantifying individual heterogeneity in the spread of infectious diseases. American Journal of Epidemiology, Vol. 177, pp. 474-486.


  16. Unkel S. and Farrington C. P. (2012): A new measure of time-varying association for shared frailty models with bivariate current status data. Biostatistics, Vol. 13, pp. 665-679.


  17. Unkel S., Farrington C. P., Garthwaite P. H., Robertson C. and Andrews N. (2012): Statistical methods for the detection of infectious disease outbreaks: a review. Journal of the Royal Statistical Society Series A, Vol. 175, pp. 49-82.


  18. Farrington C. P., Unkel S. and Anaya-Izquierdo K. (2012): The relative frailty variance and shared frailty models. Journal of the Royal Statistical Society Series B, Vol. 74, pp. 673-696.


  19. Trendafilov N. T. and Unkel S. (2011): Exploratory factor analysis of data matrices with more variables than observations. Journal of Computational and Graphical Statistics, Vol. 20, pp. 874-891.


  20. Unkel S., Hannachi A., Trendafilov N. T., Jolliffe I. T. (2011): Independent component analysis of three-way data with an application to atmospheric science. Journal of Agricultural, Biological, and Environmental Statistics, Vol. 16, pp. 319-338.


  21. Unkel S. and Trendafilov, N. T. (2010): Simultaneous parameter estimation in exploratory factor analysis: An expository review. International Statistical Review, Vol. 78, pp. 363-382.


  22. Unkel, S. and Trendafilov N. T. (2010): A majorization algorithm for simultaneous parameter estimation in robust exploratory factor analysis. Computational Statistics & Data Analysis, Vol. 54, pp. 3348-3358.


  23. Unkel S., Trendafilov N. T., Hannachi A., Jolliffe I. T. (2010): Independent exploratory factor analysis with application to atmospheric science data. Journal of Applied Statistics, Vol. 37, pp. 1847-1862.


  24. Hannachi A., Unkel S., Trendafilov N. T., Jolliffe I. T. (2009): Independent component analysis of climate data: A new look at EOF rotation. Journal of Climate, Vol. 22, No. 11, pp. 2797-2812.


  25. Unkel S. and Trendafilov N. T. (2009): Factor analysis as data matrix decomposition: A new approach for quasi-sphering in noisy ICA. In: Adali T. et al. (Eds.): Proceedings of the 8th International Conference on Independent Component Analysis and Signal Separation (ICA 2009), Lecture Notes in Computer Science 5441, Springer: Berlin, Heidelberg, pp. 163-170.


  26. Unkel S. and Trendafilov N. T. (2007): Noisy Independent Component Analysis as a Method of Rotating the Factor Scores. In: Davies M. E. et al. (Eds.): Proceedings of the 7th International Conference on Independent Component Analysis and Signal Separation (ICA 2007), Lecture Notes in Computer Science 4666, Springer: Berlin, Heidelberg, pp. 810-817.