Statistical and dynamical models in biology and medicine

October 21-22, 2010, DKFZ Heidelberg

This workshop intends to bring together researchers who are interested in modeling and analysis of biological systems, bioinformatics, statistical methods, and systems biology, with applications in biology and medicine. See also the flyer.

Confirmed speakers:

For the full program download the abstract book.

Registration is closed.

Preliminary Workshop program:
 Thursday, Oct. 21
12:30 Session I (Chair: Ingo Roeder) Dynamical Modeling
12:30-13:25 Keynote: Olaf Wolkenhauer A Stem Cell Niche Dominance Theorem
13:25-13:45 Ingmar Glauche Molecular decision making in embryonic and adult stem cells
13:45-14:05 Patrick Weber Parameter Estimation and Identifiability of Biological Networks Using Relative Data
14:05-14:25 Daniella Schittler Switch models for cell differentiation: Bifurcation analysis reveals distinct switching properties
14:25-16:00 Poster session I + coffee  
16:00 Session II (Chair: Tim Beißbarth) Network reconstruction
16:00-16:55 Keynote: Markus Kalisch Extracting causal information from observational data: Achievements and Challenges
16:55-17:15 Michael Weber Network Inference from Transcriptome Monitoring of the Response of Synovial Fibroblasts from Rheumatoid Arthritis and Osteoarthritis Patients to TNF-alpha and TGF-beta
17:15-17:35 Miriam Lohr Extracting differential regulatory sub-networks from genome-wide Microrarray expression data
17:35-17:55 Christian Bender Dynamic Deterministic Effects Propagation Networks for learning signalling pathways from longitudinal protein array data
17:55-18:15 Hans Kestler Reducing the complexity of Boolean network search via binarization
18:15-19:30 Poster session II + drinks  
20.00 Get together (Pub, Brauhaus Vetter)  
 Friday, Oct 22
9:00 Session III (Chair: Julien Gagneur) Systems Genetics
9:00-9:55 Keynote: Oliver Stegle Association mapping of complex phenotypes using models at a systems level
9:55-10:15 Andreas Beyer Disentangling complex regulatory traits in QTL analysis
10:15-10:35 Bernd Fischer Mapping Gene Function through Synthetic Genetic Interaction Analysis by RNAi
10:35-10:55 Katrin Knies Comparison and model selection for disease progression models
11:00-11:30 Coffee
11:30 Session IV (Chair: Nicole Radde) Open topics
11:30-11:50 Bartek Wilczynki Bayesian Framework For Predicting Spatio-Temporal Expression Patterns During Development
11:50-12:10 Rodrigo Assar Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method
12:10-12:30 Andreas Raue Addressing Parameter Identifiability by Model-Based Experimentation
12:30-12:50 Achim Tresch The dynamics of mRNA synthesis and degradation in response to osmotic stress
12:50-13:00 Workshop closing

How to find us

We meet in the big lecture hall at the DKFZ main building, The DKFZ lies on the science campus of the university of Heidelberg, Im Neuenheimer Feld 280.

The closest airport (by time, not by distance) is Frankfurt/Main. It is approximately 90km away, but has a nice high-speed train connection to Heidelberg via Mannheim. Travel by train is about 1 hour. Other airports would be Karlsruhe/Baden Airport and Stuttgart. Travel directions are at the DKFZ web site, too.


You will need to make your own accommodation arrangements.

Further information

Please contact Tim Beißbarth:

The workshop is jointly organized by the Gmds/IBS Working Groups 'Statistical methods in bioinformatics' and 'Mathematical models in medicine' by Tim Beißbarth, Universität Göttingen; Julien Gagneur, EMBL Heidelberg; Nicole Radde, Universität Stuttgart; Ingo Roeder, Universität Dresden. Local organisation at DKFZ-Heidelberg is made possible by Christian Bender, Mark Zapatka, Axel Benner, Benedikt Brors and Holger Sültmann.